THRA 抗体 (N-Term)
Quick Overview for THRA 抗体 (N-Term) (ABIN6657352)
抗原
See all THRA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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Supplier Product No.
- 209-301-e67
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Supplier
- Rockland
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原理
- Thyroid Hormone Receptor alpha 1/2 Antibody
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交叉反应 （详细）
- Anti-Thyroid Hormone Receptor alpha 1/2 antibody is directed against human Thyroid Hormone Receptor alpha 1/2 protein and is specific for the TR-α1 and the TR-α2 proteins.
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纯化方法
- Anti-Thyroid Hormone Receptor alpha 1/2 Antibody was purified by Protein G chromatography from cell culture supernatant followed by extensive dialysis against the buffer stated above.
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免疫原
- Anti-Thyroid Hormone Receptor alpha 1/2 Monoclonal Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region of Thyroid Hormone Receptor alpha.
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亚型
- IgG1
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anti-Thyroid Hormone Receptor, alpha (THRA) (AA 87-178) antibody
THRA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, alpha (THRA) antibodyTHRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 unconjugated
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (HRP)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 HRP
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (FITC)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 FITC
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (Biotin)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 Biotin
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (PE)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 PE
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (PerCP)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 PerCP
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (APC)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 APC
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (Atto 488)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 Atto 488
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (Atto 594)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 Atto 594
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应用备注
- Optional[Neutralization_Dilution]: 1:1,000
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说明
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Thyroid Hormone Receptor alpha 1/2 antibody has been tested for use in Western Blot. The expected bands in western blot are 50kDa for TR-α1 and 58 kDa for the TR-α2 proteins. Researchers should determine optimal titers for applications that are not stated below.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- THRA (Thyroid Hormone Receptor, alpha (THRA))
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别名
- THRA
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背景
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Synonyms: mouse anti-Thyroid Hormone Receptor alpha 1/2 Antibody, mouse anti-Thra antibody, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alpha
Background: Thyroid Hormone Receptor alpha 1/2 antibody detects TRα1 and TRα2. Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory. Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRα1, TRα2, TRβ1 and TRβ2. TRα1, TRβ1 and TRβ2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain. Anti-TRα1/ TRα2 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: THRA
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基因ID
- 7067
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UniProt
- P10827
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development
抗原
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