THRA 抗体 (N-Term)
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- 抗原 See all THRA 抗体
- THRA (Thyroid Hormone Receptor, alpha (THRA))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This THRA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- Supplier Product No.
- 209-301-e67
- Supplier
- Rockland
- 原理
- Thyroid Hormone Receptor alpha 1/2 Antibody
- 交叉反应 (详细)
- Anti-Thyroid Hormone Receptor alpha 1/2 antibody is directed against human Thyroid Hormone Receptor alpha 1/2 protein and is specific for the TR-α1 and the TR-α2 proteins.
- 纯化方法
- Anti-Thyroid Hormone Receptor alpha 1/2 Antibody was purified by Protein G chromatography from cell culture supernatant followed by extensive dialysis against the buffer stated above.
- 免疫原
- Anti-Thyroid Hormone Receptor alpha 1/2 Monoclonal Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region of Thyroid Hormone Receptor alpha.
- 克隆位点
- 2103
- 亚型
- IgG1
- Top Product
- Discover our top product THRA Primary Antibody
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- 应用备注
- Optional[Neutralization_Dilution]: 1:1,000
- 说明
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Thyroid Hormone Receptor alpha 1/2 antibody has been tested for use in Western Blot. The expected bands in western blot are 50kDa for TR-α1 and 58 kDa for the TR-α2 proteins. Researchers should determine optimal titers for applications that are not stated below.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- THRA (Thyroid Hormone Receptor, alpha (THRA))
- 别名
- THRA (THRA 产品)
- 背景
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Synonyms: mouse anti-Thyroid Hormone Receptor alpha 1/2 Antibody, mouse anti-Thra antibody, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alpha
Background: Thyroid Hormone Receptor alpha 1/2 antibody detects TRα1 and TRα2. Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory. Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRα1, TRα2, TRβ1 and TRβ2. TRα1, TRβ1 and TRβ2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain. Anti-TRα1/ TRα2 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: THRA
- 基因ID
- 7067
- UniProt
- P10827
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development
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