DLG4 抗体 (Internal Region)
Quick Overview for DLG4 抗体 (Internal Region) (ABIN6656694)
抗原
See all DLG4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Internal Region
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Supplier Product No.
- 200-301-g34
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Supplier
- Rockland
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原理
- PSD95 Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with PSD-95 from Mouse, Human, and rat based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-PSD-95 Antibody was purified by Protein G chromatography.
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过滤
- Sterile filtered
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免疫原
- PSD95 Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to an internal region of human PSD95/SAP90.
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亚型
- IgG2a
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anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA, mIHC 宿主: 小鼠 Monoclonal 6G6 unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) (C-Term) antibodyDLG4 适用: 大鼠, 人, 小鼠 WB, IHC, ELISA, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibodyDLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (HRP)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 HRP
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (FITC)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 FITC
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Biotin)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 Biotin
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PE)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 PE
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PerCP)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 PerCP
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (APC)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 APC
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Atto 488)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 Atto 488
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应用备注
- Optional[Neutralization_Dilution]: 1:1000
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说明
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Anti-PSD-95 Antibody is tested for use in WB, IHC, Immuno-gold EM, and IP. Expect a band approximately ~95-110kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
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别名
- PSD-95
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背景
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Synonyms: DLG4, SAP90, Synapse-associated protein 90, Postsynaptic density protein 95, Disks large homolog 4
Background: Postsynaptic Density protein 95 (PSD95), also known as Synapse associated protein 90 kDa, is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. PSD95 is a scaffolding protein and is involved in the assembly and function of the postsynaptic density complex. These family members consist of an N-terminal variable segment followed by three amino-terminal PDZ domains, an upstream SH3 domain and an inactive carboxyl-terminal guanylate kinase (GK) domain. The first and second PDZ domain localize NMDA receptors and K+ channels to synapses, and the third binds to neuroligins which are neuronal cell adhesion molecules that interact with b-neurexins and form intercellular junctions. PSD-95 also binds to neuronal nitric oxide synthase, possibly through interactions between PDZ domains present on both proteins. Thus different PDZ domains of PSD-95 might be specialized for distinct functions. PSD95 participates in synaptic targeting of AMPA receptors through an indirect manner involving Stargazin and related transmembrane AMPA receptor regulatory proteins (TARPs). The protein is implicated in experience dependent plasticity and plays an indispensable role in learning. Mutations in PSD95 are associated with autism.
Gene Name: DLG4
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基因ID
- 1742
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NCBI登录号
- NP_001122299
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UniProt
- P78352
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途径
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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