CNTNAP2 抗体 (Extracellular Domain)
Quick Overview for CNTNAP2 抗体 (Extracellular Domain) (ABIN6656679)
抗原
See all CNTNAP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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Supplier Product No.
- 200-301-f04
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Supplier
- Rockland
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原理
- CASPR2 Antibody
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交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with CASPR2 from Mouse, Human, and Rat based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-CASPR2 Antibody was purified by Protein G chromatography.
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过滤
- Sterile filtered
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免疫原
- CASPR2 Antibody was produced in mice by repeated immunizations with a fusion protein (extracellular domain) of human CASPR2.
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亚型
- IgG2a
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应用备注
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Immunoprecipitation_Dilution: User Optimized
Immunohistochemistry_Dilution: 0.1-1.0 μg/mL
IF_Microscopy_Dilution: 1.0-10 μg/mL
Western_Blot_Dilution: 1 μg/mL
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说明
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Anti-CASPR2 Antibody is tested in WB, IP, and IHC. Expect a band approximately ~180kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 1X PBS, pH 7.4
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.09 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
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别名
- CASPR2
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背景
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Synonyms: Cntnap2, CNTP2, Contactin associated protein like 2, Cell recognition molecule Caspr2, CASPR2, KIAA0868
Background: Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex (3). Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.
Gene Name: CNTNAP2
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基因ID
- 26047
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NCBI登录号
- NP_054860
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UniProt
- Q9UHC6
抗原
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