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CNTNAP2 抗体 (Extracellular Domain)

This 小鼠 单克隆 antibody specifically detects CNTNAP2 in WB, IHC, IP 和 FM. It exhibits reactivity toward 人.
Rockland
产品编号 ABIN6656679
Supplier Product No.: 200-301-f04
发货至: 中国
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Quick Overview for CNTNAP2 抗体 (Extracellular Domain) (ABIN6656679)

抗原

See all CNTNAP2 抗体
CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

适用

  • 51
  • 20
  • 5

宿主

  • 43
  • 9
小鼠

克隆类型

  • 44
  • 8
单克隆

标记

  • 19
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CNTNAP2 antibody is un-conjugated

应用范围

  • 41
  • 17
  • 15
  • 10
  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

克隆位点

S67-25
  • 抗原表位

    • 16
    • 8
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain

    Supplier Product No.

    200-301-f04

    Supplier

    Rockland

    原理

    CASPR2 Antibody

    交叉反应 (详细)

    A BLAST analysis was used to suggest cross-reactivity with CASPR2 from Mouse, Human, and Rat based on 100 % homology with the immunizing sequence.

    纯化方法

    Anti-CASPR2 Antibody was purified by Protein G chromatography.

    过滤

    Sterile filtered

    免疫原

    CASPR2 Antibody was produced in mice by repeated immunizations with a fusion protein (extracellular domain) of human CASPR2.

    亚型

    IgG2a
  • 应用备注

    Immunoprecipitation_Dilution: User Optimized

    Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

    IF_Microscopy_Dilution: 1.0-10 μg/mL

    Western_Blot_Dilution: 1 μg/mL

    说明

    Anti-CASPR2 Antibody is tested in WB, IP, and IHC. Expect a band approximately ~180kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 1X PBS, pH 7.4

    Stabilizer: 50 % (v/v) Glycerol

    Preservative: 0.09 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

    别名

    CASPR2

    背景

    Synonyms: Cntnap2, CNTP2, Contactin associated protein like 2, Cell recognition molecule Caspr2, CASPR2, KIAA0868

    Background: Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex (3). Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.

    Gene Name: CNTNAP2

    基因ID

    26047

    NCBI登录号

    NP_054860

    UniProt

    Q9UHC6
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