Reticulon 4 抗体
Quick Overview for Reticulon 4 抗体 (ABIN6656584)
抗原
See all Reticulon 4 (RTN4) 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 100-401-h97
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Supplier
- Rockland
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原理
- Nogo-A B Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with Anti-Nogo-A B from human, mouse, and rat based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-Nogo A/B Antibody is sera.
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免疫原
- Nogo-A/B Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic sequence corresponding to internal Nogo-A human protein.
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亚型
- IgG
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anti-Reticulon 4 (RTN4) (AA 501-515) antibody
RTN4 适用: 人, 猴 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 14-30) antibodyRTN4 适用: 人, 小鼠, 大鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 301-400) antibodyRTN4 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 251-357) antibodyRTN4 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 28-58) antibodyRTN4 适用: 人 WB 宿主: 兔 Polyclonal RB54371 unconjugated
anti-Reticulon 4 (RTN4) (AA 81-130) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 猴, 马, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (AA 254-303) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 猴, 马, Pig, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (Center) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 4 (RTN4) (Middle Region) antibodyRTN4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 马, 豚鼠, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA_Dilution: User Optimized
Immunohistochemistry_Dilution: 1:100
IF_Microscopy_Dilution: User Optimized
Western_Blot_Dilution: 1:500-1:2000
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说明
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Anti-Nogo A/B Antibody has been tested by WB, ELISA, ICC/IF, IHC, IHC-P. Expect a band approximately 48-50kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store Nogo A B antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- Reticulon 4 (RTN4)
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别名
- Nogo-A B
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背景
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Synonyms: KIAA0886, NOGO, Reticulon-4, Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, NSP, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5
Background: Nogo B 1/2 is a novel myelin-associated, intermediate-length splice variant of Nogo belonging to the reticulon family. It is a multi domain neurite growth inhibitory protein containing several discrete regions with growth inhibitory functions and is a component of the CNS myelin that prevents axonal regeneration in the adult vertebrate CNS. Nogo B1/2 along with NGBR mediated chemotaxis in HUVECs and induced tube formation in 3-dimensional cultures. It is mostly found in intact blood vessels, smooth muscle cells, and endothelial cell, with its N-terminus oriented extracellularly and is a regulator of vascular homeostasis and remodeling. It plays an important role in sporadic and familial amyotrophic lateral sclerosis. Anti-Nogo A/B is ideal for researchers interested in Neurobiology research.
Gene Name: RTN4
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基因ID
- 57142
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NCBI登录号
- NP_008939
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UniProt
- Q9NQC3
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途径
- Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
抗原
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