Aquaporin 4 抗体 (C-Term)
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- 抗原 See all Aquaporin 4 (AQP4) 抗体
- Aquaporin 4 (AQP4)
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aquaporin 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Fluorescence Microscopy (FM)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Anti-Aquaporin 4 Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Aquaporin 4 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Other species not yet tested. Cross-reactivity with Aquaporin 4 from other sources has not been determined. Channels and Transporters research.
- 免疫原
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Immunogen: Aquaporin 4 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the C-terminal region.
Immunogen Type: Peptide
- 亚型
- IgG
- Top Product
- Discover our top product AQP4 Primary Antibody
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- 应用备注
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Application Note: Anti-Aquaporin 4 Antibody is suitable for use in WB and IF microscopy. Expect a band approximately ~35 kDa on specific lysates. May detect larger glycosylated bands ~50 kDa. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1:1000-4000
IF Microscopy Dilution: 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
0.1 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- Aquaporin 4 (AQP4)
- 别名
- Aquaporin 4 (AQP4 产品)
- 别名
- zgc:100922 antibody, si:ch211-192k9.1 antibody, AQP4 antibody, LOC100232616 antibody, HMIWC2 antibody, MIWC antibody, WCH4 antibody, AQP-4 antibody, AQP4.M23 antibody, MIWC2 antibody, Miwc antibody, aquaporin-4 antibody, aquaporin 4 antibody, aquaporin 4 L homeolog antibody, aqp4 antibody, AQP4 antibody, aqp4.L antibody, Aqp4 antibody
- 背景
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Synonyms: AQP4, Aquaporin-4, Mercurial-insensitive water channel, MIWC, WCH4
Background: Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins. Aquaporin 4 is constitutively expressed in the basolateral cell membrane of princinpal collecting duct cells in the kidney and provide a pathway for water to exit these cells. It is also expressed in astrocytes and is upregulated by direct insult to the CNS. Aquaporin 4 has been propsed as the primary autoimmune target in neuromyelitis optica.
Gene Name: Aqp4
- 基因ID
- 25293
- NCBI登录号
- NP_036957
- UniProt
- P47863
- 途径
- Sensory Perception of Sound
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