SF3B4 抗体
Quick Overview for SF3B4 抗体 (ABIN6656066)
抗原
See all SF3B4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-301-x27
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Supplier
- Rockland
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原理
- SAP 49 Antibody
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纯化方法
- Anti-SAP 49 Antibody was purified from tissue culture supernatant by protein G chromatography.
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过滤
- Sterile filtered
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免疫原
- Anti-SAP 49 Antibody was produced in mice by repeated immunizations with a recombinant full length human SAP49 expressed in and purified from E. Coli.
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亚型
- IgG2b
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应用备注
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ELISA_Dilution: 1:20,000
Immunohistochemistry_Dilution: 1:1000
Western_Blot_Dilution: 1:2000
Other: ICC: 1:1000
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说明
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Anti-SAP 49 Antibody is tested for Western Blot, immunocytochemistry, immunohistochemistry, and is specific for the ~49kDa SAP49 protein. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
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有效期
- 12 months
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- SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
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别名
- SAP 49
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背景
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Synonyms: Splicing factor 3B subunit 4, Pre-mRNA-splicing factor SF3B 49 kDa subunit, SF3b50, Spliceosome-associated protein 49
Background: The spliceosome associated protein of 49 kDa (SAP49), also known as SF3B4, is a widely expressed nuclear splicing factor that has been shown to have RNA binding activity as well as direct interaction with SAP145. The SAP145-SAP49 complex has recently been implicated in cell cycle progression as Vpr (viral protein 1 of HIV-1) has been shown to bind SAP145 thus interfering with the proper formation and functioning of the SAP145-SAP49 complex. SAP 49 Antibody is ideal for researchers interested in cell cycle research.
Gene Name: SF3B4
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基因ID
- 10262
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NCBI登录号
- NP_005841
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UniProt
- Q15427
抗原
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