KDM5C 抗体
Quick Overview for KDM5C 抗体 (ABIN6655941)
抗原
See all KDM5C 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 100-401-w42
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Supplier
- Rockland
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原理
- JARID1C Antibody
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交叉反应 （详细）
- Cross reactivity with Jarid1c from other species not tested.
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纯化方法
- Anti-Jarid1c Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
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过滤
- Sterile filtered
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免疫原
- Anti-JARID1C Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides containing sequences from the inner part of the mouse Jarid1c protein.
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 5C (KDM5C) antibody
KDM5C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5C (KDM5C) (AA 45-324) antibodyKDM5C 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5C (KDM5C) (AA 10-261) antibodyKDM5C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5C (KDM5C) (C-Term) antibodyKDM5C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA_Dilution: 1:500
Western_Blot_Dilution: 1:1,000
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说明
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Anti-JARID1C Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 175 kDa in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: None
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- KDM5C (Lysine (K)-Specific Demethylase 5C (KDM5C))
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别名
- Jarid1c
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背景
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Synonyms: Lysine-specific demethylase 5C, Histone demethylase JARID1C, Jumonji/ARID domain-containing protein 1C, Protein SmcX, Protein Xe169, DXS1272E, JARID1C, SMCX, XE169
Background: Jarid1c is a histone demethylase which specifically demethylates lysine 4 of histone H3, thereby playing a internal role in the regulation of transcription and chromatin remodelling. Jarid1c demethylates the trimethylated and dimethylated lysine 4, but not the monomethylated form. Further, Jarid1c participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Mutations in the Jarid1c gene have been associated with X-linked mental retardation. Anti-Jarid1c Antibody is ideal for research in Epigenetics, Gene Expression and Neuroscience.
Gene Name: KDM5C
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基因ID
- 8242
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NCBI登录号
- NP_001140174
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UniProt
- P41229
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途径
- Warburg Effect
抗原
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