LOX 抗体
Quick Overview for LOX 抗体 (ABIN6655735)
抗原
See all LOX 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 100-401-h91
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Supplier
- Rockland
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原理
- Lysyl Oxidase Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with Anti-Lysyl Oxidase from human, bovine, chimpanzee, mouse and rat 100 % homology with the immunizing sequence.
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纯化方法
- Anti-Lysyl Oxidase Antibody is crude rabbit sera.
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免疫原
- Lysyl Oxidase Antibody was produced from whole rabbit serum prepared by repeated immunizations with the human protein Lysyl Oxidase at an internal amino acid sequence.
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亚型
- IgG
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anti-Lysyl Oxidase (LOX) (AA 213-417) antibody
LOX 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 22-168) antibodyLOX 适用: 人, 大鼠, 犬 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 5C4 unconjugated
anti-Lysyl Oxidase (LOX) antibodyLOX 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Lysyl Oxidase (LOX) antibodyLOX 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 207-411) antibodyLOX 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 174-417) antibodyLOX 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 23-285) antibodyLOX 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 234-260) antibodyLOX 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) (AA 163-411) antibodyLOX 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase (LOX) antibody (Biotin)LOX 适用: 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal Biotin
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应用备注
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Immunoprecipitation_Dilution: User Optimized
Immunohistochemistry_Dilution: 1:100
IF_Microscopy_Dilution: User Optimized
Western_Blot_Dilution: 1:250-1:1000
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说明
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Anti-Lysyl Oxidase antibody has been tested in WB, ICC/IF, IHC-F, IHC-P, IP. Expect a band approximately 31kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Optional[Buffer]: 50 % (v/v) Glycerol ,0.05 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- LOX (Lysyl Oxidase (LOX))
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别名
- Lysyl Oxidase
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背景
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Synonyms: Lysyl oxidase, LOX, Protein-lysine-6 oxidase
Background: Anti-Lysyl Oxidase antibody detects human Lysyl Oxidase. Lysyl Oxidase (LOX) belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of ECM. Localized both in the cytosol and nucleus, it catalyzes the oxidation and deamination of epsilon-NH2 group of lysine and hydroxylysine residues to alpha-aminoadipic-delta-semialdehyde. This is the first step that initiates the covalent cross-linking of collagen and tropoelastin resulting in the formation of insoluble collagen and elastic fibers in the extracellular matrix. LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. Deficiency of LOX is seen in certain carcinomas and 3X-linked recessive human connective tissue disorders-Cutis Laxa. Anti-Lysyl Oxidase antibody is ideal for investigators involved in cytokines and growth factors.
Gene Name: LOX
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基因ID
- 4015
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NCBI登录号
- NP_002308
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UniProt
- P28300
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途径
- SARS-CoV-2 Protein Interactome
抗原
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