Tumor Protein p73 抗体
Quick Overview for Tumor Protein p73 抗体 (ABIN6655656)
抗原
See all Tumor Protein p73 (TP73) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-301-i01
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Supplier
- Rockland
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原理
- p73 Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with Anti-p73 from Human and Mouse based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-p73 Antibody was purified by Protein G chromatography.
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免疫原
- p73 Antibody was produced in mice prepared by repeated immunizations with full-length human p73 protein.
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亚型
- IgG1 kappa
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anti-Tumor Protein P73 (TP73) (AA 167-409) antibody
TP73 适用: 人 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 2H5 unconjugated
anti-Tumor Protein P73 (TP73) (acLys321) antibodyTP73 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (Tyr221) antibodyTP73 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (pTyr99) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 1-198) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 288-317) antibodyTP73 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 1-198) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 501-631) antibodyTP73 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 167-409) antibodyTP73 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2H2 unconjugated
anti-Tumor Protein P73 (TP73) (AA 1-100) antibodyTP73 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optional[Neutralization_Dilution]: 1-3 μg/mL
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说明
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Anti-p73 Antibody is tested for use in WB, ChIP, ICC/IF, IHC, IHC-P, and IP. Expect a band approximately 70kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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别名
- p73
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背景
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Synonyms: P73, Tumor protein p73, p53-like transcription factor, p53-related protein
Background: Anti-p73 antibody detects human p73. p73 was identified as a long-lost cousin of tumor suppressor protein, p53. p73 has high homology with p53 as well as with p63, a gene implicated in the maintenance of epithelial stem cells. Significant homology between p53, p63, and p73 (approximately 63 % amino acid identity in the DNA-binding domain suggest that they may have overlapping functions in the regulation of gene expression. The targeted disruption of p73 gene leads to defects hippocampal dysgenesis, hydrocephalus, chronic inflammation and infections. Recently, spilicing variant mRNAs of p73 has been identified in MCF-7, a breast carcinoma cell line. These mRNAs code for variant p73 proteins bearing distinct carboxy-terminal structures suggesting that the carboxy-terminal region of p73 may be important for the functions of this protein. Tumor BioMarker found p73 to be upregulated in a significant fraction of anaplastic thyroid cancers, whereas it was not detectable in normal thyroid epithelial cells nor in papillary or follicular thyroid cancer. Anti-p73 antibody is ideal for investigators involved in cell cycle protein research.
Gene Name: TP73
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基因ID
- 7161
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NCBI登录号
- NP_001119712
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UniProt
- O15350
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途径
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
抗原
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