Tumor Protein p73 抗体
Quick Overview for Tumor Protein p73 抗体 (ABIN6655655)
抗原
See all Tumor Protein p73 (TP73) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-301-i00
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Supplier
- Rockland
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原理
- p73 Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with Anti-p73 from Human and Mouse based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-p73 Antibody was purified by Protein G chromatography.
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免疫原
- p73 Antibody was produced in mice prepared by repeated immunizations with full-length human p73 protein.
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亚型
- IgG1 kappa
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anti-Tumor Protein P73 (TP73) (AA 167-409) antibody
TP73 适用: 人 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 2H5 unconjugated
anti-Tumor Protein P73 (TP73) (acLys321) antibodyTP73 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (Tyr221) antibodyTP73 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (pTyr99) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 1-198) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 288-317) antibodyTP73 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 1-198) antibodyTP73 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 501-631) antibodyTP73 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P73 (TP73) (AA 167-409) antibodyTP73 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2H2 unconjugated
anti-Tumor Protein P73 (TP73) (AA 1-100) antibodyTP73 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry_Dilution: 5-15 μg/mL
Western_Blot_Dilution: 2 μg/mL
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说明
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Anti-p73 Antibody is tested for use in WB, ChIP, Flow, Flow-IC, ICC/IF, IHC, IHC-Fr, IHC-P, and IP. Expect a band approximately 70kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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别名
- p73
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背景
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Synonyms: P73, Tumor protein p73, p53-like transcription factor, p53-related protein
Background: Anti-p73 detects human p73. NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. Synthesis of IkBa is autoregulated. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g. External stimuli such as tumor necrosis factor or other cytokines initiates a signal transduction cascade that leads to the activation of IkB-kinase complex that specifically phosphorylates IkBa on Serine-32 and Serine-36. Phosphorylation of these sites leads to ubiquitination of IkBa and subsequent degradation by the 26 S proteasome. Degradation of IkBa results in unmasking of the nuclear localization signal of NF-kB dimers, which subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first gene induced following NF-kB activation is IkBa. Anti-p73 antibody is ideal for investigators involved in NFkappaB, kinase and phosphatse research.
Gene Name: TP73
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基因ID
- 7161
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NCBI登录号
- NP_001119712
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UniProt
- O15350
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途径
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
抗原
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