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CES1 抗体

Rockland 100-401-b14 CES1 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN6655641
Supplier Product No.: 100-401-b14
发货至: 中国
  • 抗原 See all CES1 抗体
    CES1 (Carboxylesterase 1 (CES1))
    适用
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    宿主
    • 35
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    克隆类型
    • 38
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    多克隆
    标记
    • 27
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    This CES1 antibody is un-conjugated
    应用范围
    • 29
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    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Supplier Product No.
    100-401-b14
    Supplier
    Rockland
    原理
    Liver Carboxylesterase-1 Antibody
    交叉反应 (详细)
    The antibody detects recombinant hCE1 in cell lysates and native Liver Carboxylesterase-1 present in human tissue or fluids in various assays (ie.
    纯化方法
    This product was prepared from monospecific antiserum by delipidation and defibrination.
    过滤
    Sterile filtered
    免疫原
    This whole rabbit serum was prepared by repeated immunizations with recombinant human Liver Carboxylesterase-1.
    亚型
    IgG
    Top Product
    Discover our top product CES1 Primary Antibody
  • 应用备注

    Immunoprecipitation_Dilution: 1:100

    ELISA_Dilution: 1:5,000 - 1:20,000

    Western_Blot_Dilution: 1:2,500 - 1:5,000

    Other: User Optimized

    说明

    This antibody has been tested for use in ELISA and western blotting and is specific for human CE1 (carboxylesterase).  Specific conditions for reactivity should be optimized by the end user.   Expect a band approximately 66 kDa in size corresponding CE1 by western blotting in the appropriate cell lysate or extract.  In western blot analysis endogenous protein present in human tissue or fluids, multiple bands of CE may appear corresponding to variable amount of glycosylation on the molecule.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    CES1 (Carboxylesterase 1 (CES1))
    别名
    CES1 (CES1 产品)
    背景

    Synonyms: rabbit anti-Liver Carboxylesterase-1 Antibody, Liver carboxylesterase 1, Acyl coenzyme A:cholesterol acyltransferase, ACAT, Monocyte/macrophage serine esterase, HMSE, Serine esterase 1, Brain carboxylesterase hBr1, Triacylglycerol hydrolase, Egasyn, Retinyl ester hydrolase, REH

    Background: Carboxylesterases (CES) are ubiquitous enzymes responsible for the hydrolysis of endogenous substrates with ester, thioester, or amide bonds and of xenobiotics (effecting detoxification or drug metabolism). Drug half-life and bioavailability may be modulated by selective inhibition of these proteins. CES1 or hCE1 (also known as acyl coenzyme A:cholesterol acyltransferase, monocyte/macrophage serine esterase, HMSE, serine esterase 1, brain carboxylesterase, triacylglycerol hydrolase, egasyn and retinyl ester hydrolase) is responsible for hydrolysis of stored cholesterol esters in macrophage foam cells and release of free cholesterol for high density lipoprotein-mediated cholesterol efflux.

    Gene Name: CES1

    基因ID
    1066, 68508965
    UniProt
    P23141
    途径
    Monocarboxylic Acid Catabolic Process
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