CXCR2 抗体 (Internal Region)
Quick Overview for CXCR2 抗体 (Internal Region) (ABIN6655456)
抗原
See all CXCR2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
Supplier Product No.
- 600-401-p54
-
Supplier
- Rockland
-
原理
- CXCR2 Antibody
-
交叉反应 (详细)
- Anti-CXCR2 antibody is directed against human CXCR2 protein.
-
纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
-
免疫原
- CXCR2 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human CXCR2.
-
亚型
- IgG
-
-
-
-
应用备注
- Optional[Neutralization_Dilution]: 0.5 μg/mL
-
说明
-
Anti-CXCR2 is tested for Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~40.8 kDa corresponding to the appropriate cell lysate or extract.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
-
Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
-
缓冲液
-
Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide
Stabilizer: 5 mg BSA
Preservative: 0.05 mg Thimerosal -
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
-
别名
- CXCR2
-
背景
-
Synonyms: CDw128b,GRO/MGSA receptor,High affinity interleukin-8 receptor B,
Background: CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries. This antibody is suitable for researchers interested in cell signaling research.
Gene Name: CXCR2
-
基因ID
- 3579
-
NCBI登录号
- NP_001161770
-
UniProt
- P25025
-
途径
- cAMP Metabolic Process
抗原
-