CD19 抗体 (APC)
Quick Overview for CD19 抗体 (APC) (ABIN6655428)
抗原
See all CD19 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-326-n24
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Supplier
- Rockland
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原理
- CD19 Allophycocyanin Antibody
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交叉反应 (详细)
- Reactivity is observed against human CD19.
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纯化方法
- Allophycocyanin conjugated CD19 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD19.
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过滤
- Sterile filtered
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免疫原
- Anti-CD19 Antibody (Monoclonal) was produced by repeated immunizations with CD19 antigen.
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亚型
- IgG1 kappa
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Labeling Ratio
- 1-2
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应用备注
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Immunohistochemistry_Dilution: User Optimized
Flow_Cytometry_Dilution: 5μL/test/1x10e5 to 1x10e8 cells
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说明
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Anti-CD19 is tested for Flow Cytometry and useful in Immunohistochemistry. Researchers should determine optimal titers for applications that are not stated.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.1 % Gelatin
Preservative: None -
储存液
- Without preservative
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储存条件
- 4 °C
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储存方法
- Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
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有效期
- 6 months
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- CD19 (CD19 Molecule (CD19))
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别名
- CD19
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背景
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Synonyms: B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD19
Background: The HIB19 antibody reacts with human CD19, 95 kDa glycoprotein which acts as a co-receptor, along with CD21, CD81 and CD225, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.The HIB19 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.
Gene Name: CD19
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基因ID
- 930
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NCBI登录号
- NP_001171569
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UniProt
- P15391
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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