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CD8 alpha 抗体 (FITC)

The 小鼠 单克隆 anti-CD8 alpha antibody is suitable to detect CD8 alpha in samples from 人. It has been validated for FACS 和 IHC.
Rockland
产品编号 ABIN6655402
Supplier Product No.: 200-302-n61
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD8 alpha 抗体 (FITC) (ABIN6655402)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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小鼠

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单克隆

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This CD8 alpha antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC)

克隆位点

HIT8a
  • Supplier Product No.

    200-302-n61

    Supplier

    Rockland

    原理

    CD8a Fluorescein Antibody

    交叉反应 (详细)

    Reactivity is observed against human CD8a, Marmoset, and chimpanzee.

    纯化方法

    Fluorescein conjugated CD8a Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD8a.

    过滤

    Sterile filtered

    免疫原

    Anti-CD8a Antibody (Monoclonal) was produced by repeated immunizations with CD8a antigen.

    亚型

    IgG1 kappa

    Labeling Ratio

    4-6
  • 应用备注

    Immunohistochemistry_Dilution: User Optimized

    Flow_Cytometry_Dilution: 5 µL/1x10e6 cells or 100μL of whole blood

    说明

    Anti-CD8a has been tested in Flow Cytometry and is useful for Immunohistochemistry. Researchers should determine optimal titers for applications that are not stated.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.2 % BSA (w/v)

    Preservative: 0.09 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.

    有效期

    6 months
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8a

    背景

    Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a

    Background: CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

    Gene Name: CD8A

    基因ID

    925

    NCBI登录号

    NP_001139345

    UniProt

    P01732

    途径

    TCR Signaling
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