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TRF2 抗体

This anti-TRF2 antibody is a 小鼠 单克隆 antibody detecting TRF2 in WB, ELISA, IHC, IP, IF, ChIP, FACS 和 FM. Suitable for 人.
Rockland
产品编号 ABIN6655376
Supplier Product No.: 200-301-i34
发货至: 中国

Quick Overview for TRF2 抗体 (ABIN6655376)

抗原

See all TRF2 (TERF2) 抗体
TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TRF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Flow Cytometry (FACS), Fluorescence Microscopy (FM)

克隆位点

4A794-15
  • Supplier Product No.

    200-301-i34

    Supplier

    Rockland

    原理

    TRF2 Antibody

    交叉反应 (详细)

    A BLAST analysis was used to suggest cross-reactivity with Anti-TRF2 from Human, Mouse, Muntjac (deer), and rat based on 100 % homology with the immunizing sequence.

    纯化方法

    Anti-TRF2 Antibody was purified by Protein G chromatography.

    免疫原

    TRF2 Antibody was produced in mice by repeated immunizations with a full-length TRF2 human protein.

    亚型

    IgG1 kappa
  • 应用备注

    ChIP_Dilution: User Optimized

    Immunoprecipitation_Dilution: 2 μg/10^6 cells

    ELISA_Dilution: 2 μg/mL

    Immunohistochemistry_Dilution: 5 μg/mL

    Flow_Cytometry_Dilution: User Optimized

    IF_Microscopy_Dilution: User Optimized

    Western_Blot_Dilution: 2-4 μg/mL

    说明

    Anti-TRF2 Antibody is tested for use in WB, ChIP, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, and IP. Expect a band approximately 55.6 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.05 % BSA

    Preservative: 0.05 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

    别名

    TERF2

    背景

    Synonyms: TRBF2, TRF2, Telomeric repeat-binding factor 2, TTAGGG repeat-binding factor 2, Telomeric DNA-binding protein

    Background: TRF2 antibody detects human, mouse, deer and rat TRF2. TRF2 is an ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1, contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini. The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells. Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types. Anti TRF2 antibody is ideal for investigators involved in apoptosis and chromatin research.

    Gene Name: TERF2

    基因ID

    7014

    NCBI登录号

    NP_005643

    UniProt

    Q15554

    途径

    Cell Division Cycle, Telomere Maintenance
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