S1PR4 抗体 (N-Term)
Quick Overview for S1PR4 抗体 (N-Term) (ABIN6655347)
抗原
See all S1PR4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 600-401-i18
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Supplier
- Rockland
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原理
- Edg6 Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with Edg6 from human, mouse and rat based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-Edg6 Antibody was purified by affinity chromatography.
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免疫原
- Edg6 Antibody was produced from whole rabbit serum prepared by repeated immunizations with the n-terminus amino acid portion of human Edg6 protein.
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亚型
- IgG
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anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (AA 8-37), (N-Term) antibody
S1PR4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB1829 unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (Cytoplasmic Domain) antibodyS1PR4 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (AA 301-384) antibodyS1PR4 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) antibodyS1PR4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (Cytoplasmic Domain) antibodyS1PR4 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人, 猴, 犬, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (AA 1-384) antibodyS1PR4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 4 (S1PR4) (C-Term) antibodyS1PR4 适用: 人 WB 宿主: 小鼠 Monoclonal 1 unconjugated
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应用备注
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IF_Microscopy_Dilution: 5 μg/mL
Western_Blot_Dilution: 3.0-5.0 μg/mL
Other: ICC: 5 μg/mL
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说明
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Anti-Edg6 is tested for use in WB, ICC/IF, IHC, and IHC-P. Expect a band approximately 35kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))
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别名
- Edg6
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背景
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Synonyms: EDG6, Sphingosine 1-phosphate receptor 4, S1P receptor 4, S1P4, Endothelial differentiation G-protein coupled receptor 6, Sphingosine 1-phosphate receptor Edg-6, S1P receptor Edg-6
Background: Anti-Sphingolipid Receptor Edg6 S1P4 detects human and mouse Sphingolipid Receptor Edg6 S1P4. Edg6 is a recently cloned member of the endothelial differentiation gene (EDG) G protein-coupled receptor family. It is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P), which are structurally related lysophospholipid mediators. Binding of SPP to Edg6 activates Erk, leading to the activation of the transcription factor Elk1 and thus the mitogen-activated protein kinase (MAPK) signal transduction pathway. The protein also acts as a receptor for a lipid-derived ligand. Edg6 plays an essential role in lymphocyte cell signaling. The protein is specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Human Edg6 gene is intronless and is mapped to chromosome 19p13.3 at the D19S120 marker. Anti-Sphingolipid Receptor Edg6 S1P4 antibody is ideal for investigators involved in neurobiology.
Gene Name: S1PR4
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UniProt
- O95977
抗原
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