Progesterone Receptor 抗体 (AA 412-526)
(2 references)
Quick Overview for Progesterone Receptor 抗体 (AA 412-526) (ABIN6655214)
抗原
See all Progesterone Receptor (PGR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 412-526
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Supplier Product No.
- 900-c01-b36
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Supplier
- Rockland
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原理
- Progesterone Receptor Antibody
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交叉反应 （详细）
- The antibody is specific for human Progesterone Receptor protein.
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纯化方法
- This product is clarified tissue culture supernate.
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过滤
- Sterile filtered
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免疫原
- Anti-Progesterone Receptor monoclonal antibody was produced by repeated immunizations with a recombinant protein corresponding to amino acid residues 412-526 of human Progesterone Receptor protein. The hybridoma was produced by fusing New Zealand White rabbit splenocytes and myeloma cells using conventional technology.
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亚型
- IgG
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anti-Progesterone Receptor (PGR) (AA 1-110) antibody
PGR 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 5D10 unconjugated
anti-Progesterone Receptor (PGR) antibodyPGR 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Progesterone Receptor (PGR) (AA 166-411) antibodyPGR 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2E4B9 unconjugated
anti-Progesterone Receptor (PGR) antibodyPGR 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor (PGR) (AA 1-250) antibodyPGR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor (PGR) (AA 501-600) antibodyPGR 适用: 人 WB, ELISA, IHC (p), IF (p), IF (cc), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor (PGR) (pSer190) antibodyPGR 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor (PGR) (AA 483-571) antibodyPGR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PGR-2694 unconjugated
anti-Progesterone Receptor (PGR) (pSer400) antibodyPGR 适用: 人, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor (PGR) (pSer294) antibodyPGR 适用: 人, 大鼠, 小鼠, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA_Dilution: 1:10,000
Immunohistochemistry_Dilution: 1:400
Western_Blot_Dilution: 1:200-1:500
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说明
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This monoclonal antibody contains TBS/1% BSA. Anti-Progesterone Receptor has been tested in IHC and is suitable for ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 116 kDa in size corresponding to PgR isoform B (the 'canonical' sequence) protein by western blotting in the appropriate cell lysate or extract. Progesterone Receptor is found in human Breast ductal carcinoma and is a nuclear protein. For immunohistochemistry, samples should be formalin fixed and paraffin embedded. Deparaffinize slides using xylene or xylene alternatives and graded alcohols. Staining requires boiling of sections in 10 mM citrate buffer pH 6.0 for 10 min followed by cooling at RT for 20 min.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: See application note.
Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Preservative: 0.1 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.
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有效期
- 6 months
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: "Development of new rabbit monoclonal antibody to estrogen receptor: immunohistochemical assessment on formalin-fixed, paraffin-embedded tissue sections." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 13, Issue 1, pp. 91-5, (2005) (PubMed).
: "Estimation of hormone receptor status in fine-needle aspirates and paraffin-embedded sections from breast cancer using the novel rabbit monoclonal antibodies SP1 and SP2." in: Diagnostic cytopathology, Vol. 29, Issue 4, pp. 207-11, (2004) (PubMed).
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: "Development of new rabbit monoclonal antibody to estrogen receptor: immunohistochemical assessment on formalin-fixed, paraffin-embedded tissue sections." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 13, Issue 1, pp. 91-5, (2005) (PubMed).
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- Progesterone Receptor (PGR)
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别名
- Progesterone Receptor
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背景
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Synonyms: rabbit anti-Progesterone Receptor Antibody, PgR, PR, nuclear receptor subfamily 3 group C member 3
Background: The PGR gene encodes a member of the steroid receptor superfamily referred to as progesterone receptor (also known as PgR, PR and nuclear receptor subfamily 3 group C member 3). Progesterone receptor mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. Ideal for Cancer, Chromatin & Nuclear Signaling and Signal Transduction research.
Gene Name: PGR
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基因ID
- 5241
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UniProt
- P06401
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途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
抗原
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