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CD8 alpha 抗体 (FITC)

This anti-CD8 alpha antibody is a 小鼠 单克隆 antibody detecting CD8 alpha in FACS. Suitable for 人.
Rockland
产品编号 ABIN6655185
Supplier Product No.: 200-302-m64
发货至: 中国

Quick Overview for CD8 alpha 抗体 (FITC) (ABIN6655185)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD8 alpha antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

RPA-T8
  • Supplier Product No.

    200-302-m64

    Supplier

    Rockland

    原理

    CD8 Fluorescein Antibody

    交叉反应 (详细)

    Reactivity is observed against human CD8 and chimpanzee.

    纯化方法

    Fluorescein conjugated CD8 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against human CD8.

    过滤

    Sterile filtered

    免疫原

    Anti-CD8 Antibody (Monoclonal) was produced by repeated immunizations with CD8 antigen.

    亚型

    IgG1 kappa

    Labeling Ratio

    2-8
  • 应用备注

    Optional[Neutralization_Dilution]: 10 μL/10^6 cells (0.25 μg)

    说明

    Anti-CD8 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.1 % Gelatin

    Preservative: 0.09 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.

    有效期

    6 months
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8A

    背景

    Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL

    Background: CD8 is a cell surface glycoprotein expressing on thymocytes subsets and cytotoxic T cells and is either a homodimer of two alpha chains, or a heterodimer of one alpha and one beta chain. It acts as a coreceptor during T cell activation through the binding of MHC Class I molecules and is found on T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 associates with LCK with the help of a zinc clasp structure and down-regulates the production of major Th2-type cytokines. CD8 is also known to recruit pUL97 thereby inducing dissolution of the nuclear lamina and facilitating the nuclear export of viral capsids.

    Gene Name: CD8

    基因ID

    925

    NCBI登录号

    NP_001139345

    UniProt

    P01732

    途径

    TCR Signaling
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