CD8 alpha 抗体 (FITC)
Quick Overview for CD8 alpha 抗体 (FITC) (ABIN6655185)
抗原
See all CD8 alpha (CD8A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
Supplier Product No.
- 200-302-m64
-
Supplier
- Rockland
-
原理
- CD8 Fluorescein Antibody
-
交叉反应 (详细)
- Reactivity is observed against human CD8 and chimpanzee.
-
纯化方法
- Fluorescein conjugated CD8 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against human CD8.
-
过滤
- Sterile filtered
-
免疫原
- Anti-CD8 Antibody (Monoclonal) was produced by repeated immunizations with CD8 antigen.
-
亚型
- IgG1 kappa
-
Labeling Ratio
- 2-8
-
-
-
-
应用备注
- Optional[Neutralization_Dilution]: 10 μL/10^6 cells (0.25 μg)
-
说明
-
Anti-CD8 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.1 % Gelatin
Preservative: 0.09 % (w/v) Sodium Azide -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store vial at 4° C prior to opening. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. DO NOT FREEZE. This product is light sensitive.
-
有效期
- 6 months
-
-
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
-
别名
- CD8A
-
背景
-
Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL
Background: CD8 is a cell surface glycoprotein expressing on thymocytes subsets and cytotoxic T cells and is either a homodimer of two alpha chains, or a heterodimer of one alpha and one beta chain. It acts as a coreceptor during T cell activation through the binding of MHC Class I molecules and is found on T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 associates with LCK with the help of a zinc clasp structure and down-regulates the production of major Th2-type cytokines. CD8 is also known to recruit pUL97 thereby inducing dissolution of the nuclear lamina and facilitating the nuclear export of viral capsids.
Gene Name: CD8
-
基因ID
- 925
-
NCBI登录号
- NP_001139345
-
UniProt
- P01732
-
途径
- TCR Signaling
抗原
-