Rho-related GTP-binding protein 抗体
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北京 101111
Quick Overview for Rho-related GTP-binding protein 抗体 (ABIN6655039)
抗原
See all Rho-related GTP-binding protein (RhO (pan)) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-301-e29
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Supplier
- Rockland
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原理
- Rhodopsin Antibody
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交叉反应 （详细）
- Anti-Rhodopsin antibody is directed against bovine Rhodopsin.
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纯化方法
- Rhodopsin antibodies are Protein G purified from cell culture supernantant.
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免疫原
- Anti-Rhodopsin Monoclonal Antibody was produced in mouse by repeated immunizations with purified native bovine rhodopsin.
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亚型
- IgG1
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anti-Rho-related GTP-binding protein (RhO (pan)) (C-Term) antibody
RhO (pan) 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) antibodyRhO (pan) 适用: 人, 大鼠, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) (Internal Region) antibodyRhO (pan) 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) (Ser334) antibodyRhO (pan) 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) (AA 62-93) antibodyRhO (pan) 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB52315 unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) antibodyRhO (pan) 适用: 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) (AA 310-339), (C-Term) antibodyRhO (pan) 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB36659 unconjugated
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应用备注
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Immunohistochemistry_Dilution: 1:100
Western_Blot_Dilution: 1:1000
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说明
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Anti-Rhodopsin antibody has been tested in Western Blot and Immunohistochemistry. Expect a band of approximately 39 kDa in size corresponding to the rhodopsin proteins in Western blot in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- Rho-related GTP-binding protein (RhO (pan))
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别名
- RHO
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背景
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Synonyms: OPN2, Rhodopsin, RHO, Anti-Rhodopsin monoclonal, photoreceptor proteins
Background: Rhodopsin antibody detects rhodopsin which is a photoreceptor protein found in retinal rods. It is a complex formed by the binding of retinaldehyde, the oxidized form of retinol, to the protein opsin and undergoes a series of complex reactions in response to visible light resulting in the transmission of nerve impulses to the brain. Mutation of the rhodopsin gene is a major contributor to various retinopathies such as retinitis pigmentosa. The disease-causing protein generally aggregates with ubiquitin in inclusion bodies, disrupts the intermediate filament network and impairs the ability of the cell to degrade non-functioning proteins which leads to photoreceptor apoptosis. Other mutations on rhodopsin lead to X-linked congenital stationary night blindness, mainly due to constitutive activation, when the mutations occur around the chromophore binding pocket of rhodopsin. Several other pathological states relating to rhodopsin have been discovered including poor post-Golgi trafficking, dysregulative activation, rod outer segment instability and arrestin binding. Anti-Rhodopsin Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: RHO
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基因ID
- 509933
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UniProt
- P02699
抗原
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