IL3RA 抗体 (AA 26-171)
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北京 101111
Quick Overview for IL3RA 抗体 (AA 26-171) (ABIN6654878)
抗原
See all IL3RA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 26-171
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纯化方法
- Purified
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纯度
- Protein A affinity chromatography
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免疫原
- A portion of amino acids 26-171 was used as the immunogen for the recombinant CD123 antibody.
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亚型
- IgG kappa
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应用备注
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Optimal dilution of the recombinant CD123 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) -
限制
- 仅限研究用
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant CD123 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
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别名
- IL3RA / CD123
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背景
- CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.
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途径
- JAK/STAT Signaling
抗原
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