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CD81 抗体

The 兔 单克隆 anti-CD81 antibody (Clone C81-2885R) (ABIN6654863) specifically detects CD81 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN6654863
发货至: 中国
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Room 801-803
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Quick Overview for CD81 抗体 (ABIN6654863)

抗原

See all CD81 抗体
CD81

适用

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克隆类型

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单克隆

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This CD81 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

C81-2885R
  • 纯化方法

    Purified

    纯度

    Protein A affinity chromatography

    免疫原

    A Burkitt lymphoma derived B-cell line was used as the immunogen for the recombinant CD81 antibody.

    亚型

    IgG kappa
  • 应用备注

    Optimal dilution of the recombinant CD81 antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

    限制

    仅限研究用
  • 缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant CD81 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    CD81

    别名

    CD81

    背景

    Recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

    途径

    Inositol Metabolic Process, Hepatitis C
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