Recombinant GP2 抗体 (AA 35-179)
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Quick Overview for Recombinant GP2 抗体 (AA 35-179) (ABIN6654854)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 35-179
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原理
- Recombinant Glycoprotein 2 Antibody / GP2 / ZAP75 (azide and preservative free)
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纯化方法
- Protein A affinity chromatography
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免疫原
- A partial human recombinant protein corresponding to amino acids 35-179 was used as the immunogen for the recombinant Glycoprotein 2 antibody.
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亚型
- IgG, kappa
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应用备注
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Optimal dilution of the recombinant Glycoprotein 2 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant Glycoprotein 2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
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别名
- Glycoprotein 2
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背景
- GP2 (Glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
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UniProt
- P55259
抗原
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