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Recombinant CA9 抗体

The 兔 单克隆 anti-CA9 antibody is suitable to detect CA9 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN6654742
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CA9 抗体 (ABIN6654742)

抗原

See all CA9 抗体
CA9 (Carbonic Anhydrase IX (CA9))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CA9 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

CA9-2993R
  • 原理

    Recombinant Carbonic Anhydrase 9 Antibody (azide and preservative free)

    纯化方法

    Protein A affinity chromatography

    免疫原

    Recombinant human protein was used as the immunogen for this recombinant Carbonic Anhydrase 9 antibody.

    亚型

    IgG, kappa
  • 应用备注

    The optimal dilution of the recombinant Carbonic Anhydrase 9 antibody for each application should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant Carbonic Anhydrase 9 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    CA9 (Carbonic Anhydrase IX (CA9))

    别名

    Carbonic Anhydrase 9

    背景

    Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

    UniProt

    Q16790
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