Recombinant CA9 抗体
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北京 101111
Quick Overview for Recombinant CA9 抗体 (ABIN6654742)
抗原
See all CA9 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Recombinant Carbonic Anhydrase 9 Antibody (azide and preservative free)
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纯化方法
- Protein A affinity chromatography
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免疫原
- Recombinant human protein was used as the immunogen for this recombinant Carbonic Anhydrase 9 antibody.
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亚型
- IgG, kappa
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应用备注
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The optimal dilution of the recombinant Carbonic Anhydrase 9 antibody for each application should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant Carbonic Anhydrase 9 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CA9 (Carbonic Anhydrase IX (CA9))
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别名
- Carbonic Anhydrase 9
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背景
- Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
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UniProt
- Q16790
抗原
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