Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体
Quick Overview for Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体 (ABIN6654516)
抗原
See all Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 356-475
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纯化方法
- Purified
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纯度
- Protein A affinity chromatography
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免疫原
- Human recombinant partial protein corresponding to amino acids 356-475 was used as the immunogen for this recombinant Spectrin beta III antibody.
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亚型
- IgG kappa
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anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) antibody
SPTBN2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IHC, ELISA, Coat, StM 宿主: 兔 Monoclonal SPTBN2-2894R unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, IHC, IF, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SPTBN2-1778 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人, 小鼠, 大鼠 WB, FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal SPTBN2-1584 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal SPTBN2-1583 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IHC, IF, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SPTBN2-1582 unconjugated
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人, 小鼠, 大鼠 WB, IHC, StM 宿主: 兔 Monoclonal SPTBN2-2979R unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, FACS, IHC, IF, StM 宿主: 兔 Monoclonal SPTBN2-2887R unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) antibodySPTBN2 适用: 人 WB, IHC, ELISA, Coat 宿主: 小鼠 Monoclonal rSPTBN2-1778 unconjugated Recombinant Antibody
anti-Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 643-720) antibodySPTBN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D9 unconjugated
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应用备注
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the recombinant Spectrin beta III antibody to be titered up or down for optimal performance.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Western blot: 0.5-1 μg/mL,Flow cytometry: 1-2 μg/10^6 cells in 0.1ml,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) -
限制
- 仅限研究用
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant Spectrin beta III antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
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别名
- SPTBN2 / Spectrin beta III
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背景
- Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin and spectrin are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin I (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin III is highly homologous to both spectrin I and spectrin II. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta.
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途径
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
抗原
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