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Pituitary Growth Hormone 20kDa (AA 58-187) 抗体

适用: 人 IHC (p) 宿主: 小鼠 Monoclonal rGH-1450 unconjugated
产品编号 ABIN6654365
发货至: 中国
  • 抗原
    Pituitary Growth Hormone 20kDa
    抗原表位
    AA 58-187
    适用
    宿主
    • 3
    小鼠
    克隆类型
    • 3
    单克隆
    标记
    • 3
    非结合性
    应用范围
    • 3
    • 2
    • 2
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Purified
    纯度
    Protein G affinity chromatography
    免疫原
    A human partial recombinant protein corresponding to amino acids 58-187 was used as the immunogen for this recombinant GH antibody.
    克隆位点
    RGH-1450
    亚型
    IgG1 kappa
  • 应用备注
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the recombinant GH antibody to be titered up or down for optimal performance.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
    限制
    仅限研究用
  • 缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the recombinant GH antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    Pituitary Growth Hormone 20kDa
    别名
    Growth Hormone (pituitary)
    背景
    Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
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