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Cathepsin K 抗体 (AA 163-274)

This anti-Cathepsin K antibody is a 小鼠 单克隆 antibody detecting Cathepsin K in IHC (p). Suitable for 人.
产品编号 ABIN6654326
发货至: 中国

Quick Overview for Cathepsin K 抗体 (AA 163-274) (ABIN6654326)

抗原

See all Cathepsin K (CTSK) 抗体
Cathepsin K (CTSK)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Cathepsin K antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CTSK-2791
  • 抗原表位

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    AA 163-274

    纯化方法

    Purified

    纯度

    Protein G affinity chromatography

    免疫原

    A portion of amino acids 163-274 from the human protein was used as the immunogen for the Cathepsin K antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Cathepsin K antibody to be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

    限制

    仅限研究用
  • 缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Cathepsin K antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    Cathepsin K (CTSK)

    别名

    Cathepsin K / CTSK

    背景

    The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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