Cathepsin K 抗体 (AA 163-274)
Our Local Distributor
北京 101111
Quick Overview for Cathepsin K 抗体 (AA 163-274) (ABIN6654326)
抗原
See all Cathepsin K (CTSK) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 163-274
-
纯化方法
- Purified
-
纯度
- Protein G affinity chromatography
-
免疫原
- A portion of amino acids 163-274 from the human protein was used as the immunogen for the Cathepsin K antibody.
-
亚型
- IgG
-
-
-
-
应用备注
-
Optimal dilution of the Cathepsin K antibody to be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) -
限制
- 仅限研究用
-
-
-
缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the Cathepsin K antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
-
-
- Cathepsin K (CTSK)
-
别名
- Cathepsin K / CTSK
-
背景
- The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
-
途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
-