SPTA1 抗体 (AA 356-475)
This anti-SPTA1 antibody is a 兔 单克隆 antibody detecting SPTA1 in IHC (p). Suitable for 人.
Quick Overview for SPTA1 抗体 (AA 356-475) (ABIN6654214)
抗原
SPTA1
(Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
适用
人
宿主
兔
克隆类型
单克隆
标记
This SPTA1 antibody is un-conjugated
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
克隆位点
SPTA1-2939R
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抗原表位
- AA 356-475
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纯化方法
- Purified
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纯度
- Protein A affinity chromatography
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免疫原
- A portion of amino acids 356-475 from the human protein was used as the immunogen for the recombinant Spectrin alpha 1 antibody.
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亚型
- IgG kappa
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应用备注
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Optimal dilution of the recombinant Spectrin alpha 1 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) -
限制
- 仅限研究用
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant Spectrin alpha 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- SPTA1 (Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
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别名
- SPTA1 / Spectrin alpha 1
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背景
- Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous and chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin Ia and spectrin Ib are present in erythrocytes, whereas spectrin IIa (also designated fodrin alpha) and spectrin IIb (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.
抗原
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