CCL8 抗体 (AA 24-97)
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Quick Overview for CCL8 抗体 (AA 24-97) (ABIN6654185)
抗原
See all CCL8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-97
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids G24-P97 from the mouse protein were used as the immunogen for the Mcp2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Mcp2 antibody should be determined by the researcher.\. IHC (FFPE): 1-2 μg/mL,ELISA (Capture): 1-5 μg/mL (recombinant mouse protein)
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Mcp2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
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别名
- Mcp2 / Ccl8
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背景
- CCL8, also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene. It is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans. MCP-2 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, (that are implicated in allergic responses), and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1, CCR2B, CCR3 and CCR5.
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UniProt
- Q9Z121
抗原
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