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HSPH1 抗体 (AA 653-858)

This anti-HSPH1 antibody is a 兔 多克隆 antibody detecting HSPH1 in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6654098
发货至: 中国

Quick Overview for HSPH1 抗体 (AA 653-858) (ABIN6654098)

抗原

See all HSPH1 抗体
HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This HSPH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 653-858

    纯化方法

    Antigen affinity purified

    免疫原

    Human Heat Shock Protein 105 recombinant protein (amino acids Y653-D858) was used as the immunogen for the HSP105 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the HSP105 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the HSP105 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

    别名

    HSP105

    背景

    HSP105 (HEAT-SHOCK 105/110-KD PROTEIN 1), also called HSPH1 or HSP110, is a protein that in humans is encoded by the HSPH1 gene. Immunohistochemical analysis localizes HSP105 mainly in the cytoplasm. Database analysis indicates that both HSP105 isoforms are highly conserved during evolution. By analysis of radiation hybrids and human/rodent hybrid cell lines, the HSPH1 gene is mapped to chromosome 13. Both HSP105-alpha and HSP105-beta are upregulated in HeLa cells exposed to heat shock. HSP105-alpha, but not HSP105-beta, is also upregulate in response to other cell stresses. Following heat shock, HSP105 relocalizes from a cytoplasmic to perinuclear position. Besides, HSP110 may thus constitute a major determinant for both prognosis and treatment response in colorectal cancer.

    UniProt

    Q92598
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