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HAVCR1 抗体 (AA 58-289)

This anti-HAVCR1 antibody is a 兔 多克隆 antibody detecting HAVCR1 in WB 和 ELISA (Capture). Suitable for 人.
产品编号 ABIN6654049
发货至: 中国

Quick Overview for HAVCR1 抗体 (AA 58-289) (ABIN6654049)

抗原

See all HAVCR1 抗体
HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This HAVCR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA (Capture)
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    AA 58-289

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids Q58-K289 from the human protein were used as the immunogen for the TIM1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the TIM1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,ELISA (Capture): 1-5 μg/mL (human recombinant protein)

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the TIM1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

    别名

    KIM-1 / TIM-1 / HAVCR1

    物质类

    Virus

    背景

    KIM1 (KIDNEY INJURY MOLECULE 1), also known as HAVCR1, HAVCR or TIM1, is a protein that in humans is encoded by the KIM1 gene. The gene is mapped to 5q33.3. Biochemical, mutational, and cell adhesion analyses confirm that TIM1 is capable of homophilic Tim-Tim interactions. The protein is indeed a receptor for the virus through the infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV. Using a monoclonal antibody to mouse Tim1, TIM1 is expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. Ectopic expression of TIM1 during mouse T-cell differentiation leads to production of the Th2-type cytokine Il4, but not the Th1-type cytokine Ifng. TIM1-expressing epithelial cells internalized apoptotic bodies, and the protein is directly responsible for phagocytosis in cultured primary rat tubule epithelial cells and in porcine and canine epithelial cell lines.

    UniProt

    Q96D42
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