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Dystroglycan 抗体 (C-Term)

Name: Dystroglycan 抗体 (C-Term)
SKU: ABIN658022
Availability: OutOfStock

This anti-Dystroglycan antibody is a 兔多克隆 antibody detecting Dystroglycan in WB 和 IHC (p). Suitable for 人和小鼠.

All lanes : Anti-DAG1 Antibody (C-term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: SH-SY5Y whole cell lysate Lysates/proteins at 20 μg per lane. (Dystroglycan 抗体 (C-Term))

DAG1 Antibody (C-term) ((ABIN658022 and ABIN2846960))immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. (Dystroglycan 抗体 (C-Term))

IHC (p)

All lanes : Anti-DAG1 Antibody (C-term) at 1:2000 dilution Lane 1: SH-SY5Y whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lysates/proteins at 20 μg per lane. (Dystroglycan 抗体 (C-Term))

All lanes : Anti-DAG1 Antibody (C-term) at 1:1000-1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lysates/proteins at 20 μg per lane. (Dystroglycan 抗体 (C-Term))

Anti-DAG1 Antibody (C-term) at 1:1000 dilution + NIH/3T3 whole cell lysate Lysates/proteins at 20 μg per lane. (Dystroglycan 抗体 (C-Term))

5 images

产品编号 ABIN658022

发货至: 中国

Quick Overview for Dystroglycan 抗体 (C-Term) (ABIN658022)

抗原

See all Dystroglycan (DAG1) 抗体

Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This Dystroglycan antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB33752

Discover our top product DAG1 Primary Antibody

抗原表位
15

8

6

4

2

1

1

1

1

1

1

1

1
AA 718-747, C-Term

预测反应

Pig, Rb

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This DAG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-747 amino acids from the C-terminal region of human DAG1.

亚型

Ig Fraction
anti-Dystroglycan 1 (DAG1) antibody
DAG1 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (AA 28-406) antibody
DAG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (Internal Region) antibody
Verified DAG1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (AA 31-140) antibody
DAG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A3 unconjugated

anti-Dystroglycan 1 (DAG1) (AA 726-744) antibody
DAG1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (C-Term) antibody
DAG1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (AA 721-770) antibody
DAG1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (AA 323-372) antibody
DAG1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, Bat, 小鸡, 猴, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

anti-Dystroglycan 1 (DAG1) (C-Term) antibody
DAG1 适用: 人 IHC, IHC (fro) 宿主: 小鼠 Monoclonal 43DAG1-8D5 unconjugated

anti-Dystroglycan 1 (DAG1) (AA 654-749) antibody
DAG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:2000. WB: 1:2000. WB: 1:1000-1:2000. WB: 1:1000. IHC-P: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

DAG1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

有效期

6 months
抗原

Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))

别名

DAG1

背景

Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.

分子量

97441

基因ID

1605

NCBI登录号

NP_001159400, NP_001171105, NP_001171106, NP_001171107, NP_001171108, NP_001171109, NP_001171110, NP_001171111, NP_001171112, NP_001171113, NP_001171114, NP_001171115, NP_004384

UniProt

Q14118

途径

Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus