IL2RG 抗体
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北京 101111
Quick Overview for IL2RG 抗体 (ABIN6579821)
抗原
See all IL2RG 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD132 Purified
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特异性
- The rat monoclonal antibody TUGh4 recognizes an extracellular epitope of CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes.
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交叉反应 (详细)
- Human, Canine (Dog)
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纯化方法
- Purified by protein-G affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Human CD132-transfected cell line
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亚型
- IgG2b kappa
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
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别名
- CD132
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背景
- Interleukin 2 receptor subunit gamma,CD132 / common gamma chain is an essential component of receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21, and it is critical for development of the immune system. Its mutation causes X-linked severe combined immunodeficiency disease (XSCID). CD132 is expressed on lymphocytes, NK cells, monocytes, and granulocytes. Through its cytoplasmic part which containsfour tyrosines and an SH2 domain, CD132 transcuces signal to downstream JAK/STAT pathway.,common gamma chain, IL2RG, SCIDX, IMD4
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基因ID
- 3561
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UniProt
- P31785
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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