TUBA1B 抗体 (acLys352)
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北京 101111
Quick Overview for TUBA1B 抗体 (acLys352) (ABIN6579752)
抗原
See all TUBA1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-360, acLys352
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原理
- Tubulin α (Acetyl Lys352) Antibody
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特异性
- Acetyl-Tubulin α (K352) Polyclonal Antibody detects endogenous levels of Tubulin α protein only when acetylated at K352.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized Acetyl-peptide derived from human TUBA1B around the Acetylation site of Lys352. AA range:311-360
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TUBA1B (Tubulin, alpha 1B (TUBA1B))
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别名
- TUBA1B
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背景
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Synonyms: TUBA1A, TUBA3, Tubulin alpha-1A chain, Alpha-tubulin 3, Tubulin B-alpha-1, Tubulin alpha-3 chain, TUBA1B, Tubulin alpha-1B chain, Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain, TUBA1C, TUBA6, Tubulin alpha-6 chain, TUBA3C, TUBA2, TUBA3D, Tubulin alpha-3C/D chain, Alpha-tubulin 2, Alpha-tubulin 3C/D, Tubulin alpha-2 chain, TUBA4A, TUBA1, Tubulin alpha-4A chain, Alpha-tubulin 1, Testis-specific alpha-tubulin,
Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
Gene Name: TUBA1A/TUBA1B/TUBA1C/TUBA3C/TUBA4A/TUBA8
Protein Name: Tubulin alpha-1A chain/Tubulin alpha-1B chain/Tubulin alpha-1C chain/Tubulin alpha-3C/D chain/Tubulin alpha-4A chain/Tubulin alpha-8 chain
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分子量
- 50 kDa
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基因ID
- 7846, 10376, 84790
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OMIM
- 602529
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UniProt
- Q71U36
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途径
- Microtubule Dynamics, M Phase
抗原
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