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CDKN1C 抗体 (AA 241-290)

The 兔 多克隆 anti-CDKN1C antibody is suitable to detect CDKN1C in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IF 和 ELISA.
产品编号 ABIN6579746
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CDKN1C 抗体 (AA 241-290) (ABIN6579746)

抗原

See all CDKN1C 抗体
CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

适用

  • 162
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人, 小鼠, 大鼠

宿主

  • 114
  • 65
兔

克隆类型

  • 94
  • 85
多克隆

标记

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  • 1
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This CDKN1C antibody is un-conjugated

应用范围

  • 94
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  • 50
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  • 16
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  • 4
  • 1
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Western Blotting (WB), Immunofluorescence (IF), ELISA
  • 抗原表位

    • 20
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    AA 241-290

    原理

    p57 Antibody

    特异性

    P57 Polyclonal Antibody detects endogenous levels of p57 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human p57Kip2 around the non-acetylation site of Lys278. AA range:241-290

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

    别名

    p57Kip2

    背景

    Synonyms: CDKN1C, KIP2, Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2

    Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010],

    Gene Name: CDKN1C

    Protein Name: Cyclin-dependent kinase inhibitor 1C

    分子量

    32 kDa

    基因ID

    1028

    OMIM

    600856

    UniProt

    P49918

    途径

    Cell Division Cycle, Dopaminergic Neurogenesis
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