CDKN1C 抗体 (AA 241-290)
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北京 101111
Quick Overview for CDKN1C 抗体 (AA 241-290) (ABIN6579746)
抗原
See all CDKN1C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 241-290
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原理
- p57 Antibody
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特异性
- P57 Polyclonal Antibody detects endogenous levels of p57 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human p57Kip2 around the non-acetylation site of Lys278. AA range:241-290
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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别名
- p57Kip2
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背景
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Synonyms: CDKN1C, KIP2, Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2
Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010],
Gene Name: CDKN1C
Protein Name: Cyclin-dependent kinase inhibitor 1C
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分子量
- 32 kDa
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基因ID
- 1028
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OMIM
- 600856
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UniProt
- P49918
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途径
- Cell Division Cycle, Dopaminergic Neurogenesis
抗原
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