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E2F4 抗体 (AA 61-110)

The 兔 多克隆 anti-E2F4 antibody is suitable to detect E2F4 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN6579716
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for E2F4 抗体 (AA 61-110) (ABIN6579716)

抗原

See all E2F4 抗体
E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))

适用

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  • 1
人, 小鼠, 大鼠

宿主

  • 87
  • 8
  • 2
兔

克隆类型

  • 62
  • 35
多克隆

标记

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  • 1
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This E2F4 antibody is un-conjugated

应用范围

  • 51
  • 41
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  • 17
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  • 11
  • 8
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 18
    • 13
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    • 5
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    • 3
    • 3
    • 2
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    • 1
    • 1
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    • 1
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    • 1
    AA 61-110

    原理

    E2F-4 Antibody

    特异性

    E2F-4 Polyclonal Antibody detects endogenous levels of E2F-4 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human E2F4 around the non-acetylation site of Lys96. AA range:61-110

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))

    别名

    E2F4

    背景

    Synonyms: E2F4, Transcription factor E2F4, E2F-4

    Background: The protein encoded byThis gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated ge

    Gene Name: E2F4

    Protein Name: Transcription factor E2F4

    分子量

    43 kDa

    基因ID

    1874

    OMIM

    600659

    UniProt

    Q16254

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
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