PLGRKT 抗体 (AA 1-50)
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北京 101111
Quick Overview for PLGRKT 抗体 (AA 1-50) (ABIN6579700)
抗原
See all PLGRKT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Plasminogen receptor Antibody
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特异性
- Plasminogen receptor Polyclonal Antibody detects endogenous levels of Plasminogen receptor
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human PLGRKT. AA range:1-50
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PLGRKT (Plasminogen Receptor, C-Terminal Lysine Transmembrane Protein (PLGRKT))
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别名
- PLGRKT
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背景
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Synonyms: Plasminogen receptor (KT) (Plg-R(KT))
Background: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.
Gene Name: PLGRKT
Protein Name: Plasminogen receptor
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分子量
- 17 kDa
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基因ID
- 55848
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UniProt
- Q9HBL7
抗原
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