GDF7 抗体 (AA 321-370)
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北京 101111
Quick Overview for GDF7 抗体 (AA 321-370) (ABIN6579637)
抗原
See all GDF7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 321-370
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原理
- GDF-7 Antibody
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特异性
- GDF-7 Polyclonal Antibody detects endogenous levels of GDF-7 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human GDF7. AA range:321-370
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GDF7 (Growth Differentiation Factor 7 (GDF7))
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别名
- GDF7
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背景
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Synonyms: GDF7; Growth/differentiation factor 7; GDF-7
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016],
Gene Name: GDF7
Protein Name: Growth/differentiation factor 7
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分子量
- 46 kDa
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基因ID
- 151449
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OMIM
- 604651
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UniProt
- Q7Z4P5
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途径
- Tube Formation
抗原
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