GDF6 抗体 (AA 311-360)
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北京 101111
Quick Overview for GDF6 抗体 (AA 311-360) (ABIN6579634)
抗原
See all GDF6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-360
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原理
- GDF-6 Antibody
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特异性
- GDF-6 Polyclonal Antibody detects endogenous levels of GDF-6 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human GDF6. AA range:311-360
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GDF6 (Growth Differentiation Factor 6 (GDF6))
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别名
- GDF6
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背景
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Synonyms: GDF6, GDF16, Growth/differentiation factor 6, GDF-6, Growth/differentiation factor 16
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016],
Gene Name: GDF6
Protein Name: Growth/differentiation factor 6
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分子量
- 50 kDa
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基因ID
- 392255
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OMIM
- 118100
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UniProt
- Q6KF10
抗原
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