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GDF5 抗体 (AA 361-410)

This 兔 多克隆 antibody specifically detects GDF5 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6579619
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GDF5 抗体 (AA 361-410) (ABIN6579619)

抗原

See all GDF5 抗体
GDF5 (Growth Differentiation Factor 5 (GDF5))

适用

  • 70
  • 24
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 79
  • 3
  • 3
  • 3
  • 1
兔

克隆类型

  • 83
  • 6
多克隆

标记

  • 35
  • 12
  • 8
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GDF5 antibody is un-conjugated

应用范围

  • 61
  • 34
  • 30
  • 8
  • 8
  • 7
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 10
    • 8
    • 8
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 361-410

    原理

    GDF-5 Antibody

    特异性

    GDF-5 Polyclonal Antibody detects endogenous levels of GDF-5 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human GDF5. AA range:361-410

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GDF5 (Growth Differentiation Factor 5 (GDF5))

    别名

    GDF5

    背景

    Synonyms: GDF5, CDMP1, Growth/differentiation factor 5, GDF-5, Cartilage-derived morphogenetic protein 1, CDMP-1, Radotermin

    Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. [provided by RefSeq, Aug 2016],

    Gene Name: GDF5

    Protein Name: Growth/differentiation factor 5

    分子量

    55 kDa

    基因ID

    8200

    OMIM

    601146

    UniProt

    P43026
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