CD177 抗体 (AA 361-410)
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Quick Overview for CD177 抗体 (AA 361-410) (ABIN6579571)
抗原
See all CD177 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 361-410
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原理
- CD177 Antibody
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特异性
- CD177 Polyclonal Antibody detects endogenous levels of CD177 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human CD177. AA range:361-410
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CD177 (CD177 Molecule (CD177))
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别名
- CD177
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背景
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Synonyms: CD177; NB1; PRV1; CD177 antigen; Human neutrophil alloantigen 2a; HNA-2a; NB1 glycoprotein; NB1 GP; Polycythemia rubra vera protein 1; PRV-1; CD177
Background: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014],
Gene Name: CD177
Protein Name: CD177 antigen
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分子量
- 46 kDa
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基因ID
- 57126
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OMIM
- 162860
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UniProt
- Q8N6Q3
抗原
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