LAIR1 抗体 (AA 21-70)
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北京 101111
Quick Overview for LAIR1 抗体 (AA 21-70) (ABIN6579569)
抗原
See all LAIR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-70
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原理
- CD305 Antibody
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特异性
- CD305 Polyclonal Antibody detects endogenous levels of CD305 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human LAIR1. AA range:21-70
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
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别名
- LAIR1
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背景
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Synonyms: LAIR1, CD305, Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, CD305
Background: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
Gene Name: LAIR1
Protein Name: Leukocyte-associated immunoglobulin-like receptor 1
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分子量
- 31 kDa
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基因ID
- 3903
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OMIM
- 602992
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UniProt
- Q6GTX8
抗原
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