F11R 抗体 (AA 191-240)
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北京 101111
Quick Overview for F11R 抗体 (AA 191-240) (ABIN6579557)
抗原
See all F11R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 191-240
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原理
- JAM-A Antibody
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特异性
- JAM-A Polyclonal Antibody detects endogenous levels of JAM-A protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human F11R. AA range:191-240
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- F11R (F11 Receptor (F11R))
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别名
- F11R
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背景
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Synonyms: F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321
Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008],
Gene Name: F11R
Protein Name: Junctional adhesion molecule A
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分子量
- 32 kDa
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基因ID
- 50848
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OMIM
- 605721
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UniProt
- Q9Y624
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途径
- Cell-Cell Junction Organization
抗原
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