LIFR 抗体 (AA 731-780)
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北京 101111
Quick Overview for LIFR 抗体 (AA 731-780) (ABIN6579498)
抗原
See all LIFR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 731-780
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原理
- LIFR Antibody
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特异性
- LIFR Polyclonal Antibody detects endogenous levels of LIFR protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human LIFR. AA range:731-780
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
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别名
- LIFR
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背景
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Synonyms: LIFR, Leukemia inhibitory factor receptor, LIF receptor, LIF-R, CD118
Background: leukemia inhibitory factor receptor alpha(LIFR) Homo sapiens This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5,8)(p13,q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: LIFR
Protein Name: Leukemia inhibitory factor receptor
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分子量
- '123 kDa
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基因ID
- 3977
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OMIM
- 602840
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UniProt
- P42702
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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