ITGA2 抗体 (AA 1081-1130)
Our Local Distributor
北京 101111
Quick Overview for ITGA2 抗体 (AA 1081-1130) (ABIN6579455)
抗原
See all ITGA2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1081-1130
-
原理
- Integrin α2 Antibody
-
特异性
- Integrin α2 Polyclonal Antibody detects endogenous levels of Integrin α2 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- The antiserum was produced against synthesized peptide derived from the C-terminal region of human ITGA2. AA range:1081-1130
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- ITGA2 (Integrin alpha 2 (ITGA2))
-
别名
- ITGA2
-
背景
-
Synonyms: ITGA2, CD49B, Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b
Background: integrin subunit alpha 2(ITGA2) Homo sapiens This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],
Gene Name: ITGA2
Protein Name: Integrin alpha-2
-
分子量
- '130 kDa
-
基因ID
- 3673
-
OMIM
- 176760
-
UniProt
- P17301
-
途径
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
抗原
-