DPYD 抗体 (AA 351-400)
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北京 101111
Quick Overview for DPYD 抗体 (AA 351-400) (ABIN6579410)
抗原
See all DPYD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 351-400
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原理
- DPYD Antibody
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特异性
- DPYD Polyclonal Antibody detects endogenous levels of DPYD protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human DPYD. AA range:351-400
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DPYD (Dihydropyrimidine Dehydrogenase (DPYD))
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别名
- DPYD
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背景
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Synonyms: DPYD, Dihydropyrimidine dehydrogenase [NADP(+)], DHPDHase, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase
Background: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
Gene Name: DPYD
Protein Name: Dihydropyrimidine dehydrogenase [NADP(+)]
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分子量
- 111 kDa
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基因ID
- 1806
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UniProt
- Q12882
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途径
- Ribonucleoside Biosynthetic Process
抗原
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