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DPYD 抗体 (AA 351-400)

The 兔 多克隆 anti-DPYD antibody (ABIN6579410) specifically detects DPYD in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6579410
发货至: 中国
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Quick Overview for DPYD 抗体 (AA 351-400) (ABIN6579410)

抗原

See all DPYD 抗体
DPYD (Dihydropyrimidine Dehydrogenase (DPYD))

适用

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人, 小鼠, 大鼠

宿主

  • 78
  • 3
兔

克隆类型

  • 67
  • 14
多克隆

标记

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  • 1
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This DPYD antibody is un-conjugated

应用范围

  • 66
  • 23
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  • 14
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  • 6
  • 3
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 14
    • 12
    • 5
    • 3
    • 3
    • 2
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    • 1
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    • 1
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    AA 351-400

    原理

    DPYD Antibody

    特异性

    DPYD Polyclonal Antibody detects endogenous levels of DPYD protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human DPYD. AA range:351-400

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    DPYD (Dihydropyrimidine Dehydrogenase (DPYD))

    别名

    DPYD

    背景

    Synonyms: DPYD, Dihydropyrimidine dehydrogenase [NADP(+)], DHPDHase, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase

    Background: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],

    Gene Name: DPYD

    Protein Name: Dihydropyrimidine dehydrogenase [NADP(+)]

    分子量

    111 kDa

    基因ID

    1806

    UniProt

    Q12882

    途径

    Ribonucleoside Biosynthetic Process
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