HSD17B4 抗体 (AA 41-90)
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Quick Overview for HSD17B4 抗体 (AA 41-90) (ABIN6579403)
抗原
See all HSD17B4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-90
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原理
- 17β-HSD4 Antibody
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特异性
- 17β-HSD4 Polyclonal Antibody detects endogenous levels of 17β-HSD4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the N-terminal region of human HSD17B4. AA range:41-90
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))
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别名
- HSD17B4
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背景
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Synonyms: HSD17B4, EDH17B4, Peroxisomal multifunctional enzyme type 2, MFE-2, 17-beta-hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, D-bifunctional protein, DBP, Multifunctional protein 2, MPF-2
Background: hydroxysteroid 17-beta dehydrogenase 4(HSD17B4) Homo sapiens The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
Gene Name: HSD17B4
Protein Name: Peroxisomal multifunctional enzyme type 2
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分子量
- 79 kDa
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基因ID
- 3295
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UniProt
- P51659
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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