SELPLG 抗体 (AA 1-50)
Our Local Distributor
北京 101111
Quick Overview for SELPLG 抗体 (AA 1-50) (ABIN6579396)
抗原
See all SELPLG 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-50
-
原理
- PSGL-1 Antibody
-
特异性
- PSGL-1 Polyclonal Antibody detects endogenous levels of PSGL-1 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- The antiserum was produced against synthesized peptide derived from the N-terminal region of human SELPLG. AA range:1-50
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- SELPLG (Selectin P Ligand (SELPLG))
-
别名
- SELPLG
-
背景
-
Synonyms: SELPLG, P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162
Background: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011],
Gene Name: SELPLG
Protein Name: P-selectin glycoprotein ligand 1
-
分子量
- 45 kDa
-
基因ID
- 6404
-
OMIM
- 116930
-
UniProt
- Q14242
抗原
-