PPP1R15B 抗体 (AA 411-460)
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北京 101111
Quick Overview for PPP1R15B 抗体 (AA 411-460) (ABIN6579395)
抗原
See all PPP1R15B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 411-460
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原理
- PPP1R15B Antibody
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特异性
- PPP1R15B Polyclonal Antibody detects endogenous levels of PPP1R15B protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human PPP1R15B. AA range:411-460
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亚型
- IgG
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anti-Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B) (AA 494-522), (C-Term) antibody
PPP1R15B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32305 unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B) (AA 480-529) antibodyPPP1R15B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B) (Internal Region) antibodyPPP1R15B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PPP1R15B (Protein Phosphatase 1, Regulatory Subunit 15B (PPP1R15B))
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别名
- PPP1R15B
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背景
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Synonyms: PPP1R15B, Protein phosphatase 1 regulatory subunit 15B
Background: This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular stress. The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions, while the protein coding ORF is expressed at high levels in response to stress. Continual translation of the mRNA under conditions of eukaryotic translation initiation factor 2A inactivation is thought to create a feedback loop for reactivation of the gene during recovery from stress. In addition, it has been shown that this protein plays a role in membrane traffic that is independent of translation and that it is required for exocytosis from erythroleukemia cells. Allelic variants of this gene are associated with mi
Gene Name: PPP1R15B
Protein Name: Protein phosphatase 1 regulatory subunit 15B
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分子量
- '78 kDa
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基因ID
- 84919
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OMIM
- 114280
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UniProt
- Q5SWA1
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途径
- ER-Nucleus Signaling
抗原
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