KEAP1 抗体 (AA 411-460)
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北京 101111
Quick Overview for KEAP1 抗体 (AA 411-460) (ABIN6579381)
抗原
See all KEAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 411-460
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原理
- Keap-1 Antibody
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特异性
- Keap1 Polyclonal Antibody detects endogenous levels of Keap1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human KEAP1. AA range:411-460
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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别名
- KEAP1
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背景
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Synonyms: KEAP1, INRF2, KIAA0132, KLHL19, Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2, Kelch-like protein 19
Background: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: KEAP1
Protein Name: Kelch-like ECH-associated protein 1
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分子量
- 69 kDa
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基因ID
- 9817
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OMIM
- 606016
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UniProt
- Q14145
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途径
- Maintenance of Protein Location
抗原
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