IL3RA 抗体 (AA 241-290)
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北京 101111
Quick Overview for IL3RA 抗体 (AA 241-290) (ABIN6579373)
抗原
See all IL3RA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 241-290
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原理
- IL-3Rα Antibody
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特异性
- IL-3Rα Polyclonal Antibody detects endogenous levels of IL-3Rα protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human IL3RA. AA range:241-290
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亚型
- IgG
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应用备注
- IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
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别名
- IL3RA
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背景
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Synonyms: IL3RA, IL3R, Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123
Background: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012],
Gene Name: IL3RA
Protein Name: Interleukin-3 receptor subunit alpha
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分子量
- 43 kDa
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基因ID
- 3563
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OMIM
- 109770
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UniProt
- P26951
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途径
- JAK/STAT Signaling
抗原
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